ARG41114
anti-THOP1 / Thimet Oligopeptidase antibody
anti-THOP1 / Thimet Oligopeptidase antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes THOP1 / Thimet Oligopeptidase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | THOP1 / Thimet Oligopeptidase |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-260 of Human THOP1 (NP_003240.1). |
| Conjugation | Un-conjugated |
| Alternate Names | EP24.15; TOP; Thimet oligopeptidase; MEPD_HUMAN; EC 3.4.24.15; Endopeptidase 24.15; MP78 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse skeletal muscle | ||||
| Observed Size | 79 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | THOP1 |
| Gene Full Name | thimet oligopeptidase 1 |
| Function | Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the beta-amyloid precursor protein and generate amyloidogenic fragments. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 79 kDa |
