ARG66107

anti-TL1A antibody (Biotin)

anti-TL1A antibody (Biotin) for ELISA and Human

Overview

Product Description Biotin-conjugated Rabbit Polyclonal antibody recognizes TL1A
Tested Reactivity Hu
Tested Application ELISA
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TL1A
Antigen Species Human
Immunogen E. coli derived recombinant Human TL1A.
(QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL)
Conjugation Biotin
Alternate Names TL1; Vascular endothelial cell growth inhibitor; TL1A; VEGI192A; TNF ligand-related molecule 1; VEGI; Tumor necrosis factor ligand superfamily member 15

Application Instructions

Application Suggestion
Tested Application Dilution
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG66106 as a capture antibody
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by affinity chromatography.
Buffer PBS (pH 7.2)
Concentration 1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 9966 Human TNFSF15

Swiss-port # O95150 Human Tumor necrosis factor ligand superfamily member 15

Gene Symbol TNFSF15
Gene Full Name tumor necrosis factor (ligand) superfamily, member 15
Background The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Function Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. [UniProt]
Calculated MW 28 kDa