ARG40597
anti-TM4SF1 antibody
anti-TM4SF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TM4SF1 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Predict Reactivity | Rat |
| Tested Application | IHC-P, WB |
| Specificity | At least three isoforms of TM4SF1 are known to exist; this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TM4SF1 |
| Antigen Species | Human |
| Immunogen | An 18 amino acid synthetic peptide within the first 50 amino acids of Human TM4SF1. |
| Conjugation | Un-conjugated |
| Alternate Names | Transmembrane 4 L6 family member 1; H-L6; L6; Tumor-associated antigen L6; M3S1; TAAL6; Membrane component chromosome 3 surface marker 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Human lung | ||||||
| Observed Size | 28 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P30408 Human Transmembrane 4 L6 family member 1 Swiss-port # Q64302 Mouse Transmembrane 4 L6 family member 1 |
|---|---|
| Gene Symbol | TM4SF1 |
| Gene Full Name | transmembrane 4 L six family member 1 |
| Background | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008] |
| Cellular Localization | Membrane; Multi-pass membrane protein. Note=Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519). [UniProt] |
| Calculated MW | 22 kDa |
