ARG59350
anti-TMEM158 antibody
anti-TMEM158 antibody for Western blot and Human
Overview
| Tested Reactivity | Hu |
|---|---|
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TMEM158 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide between aa. 186-218 of Human TMEM158. |
| Conjugation | Un-conjugated |
| Alternate Names | BBP; 40 kDa BINP-binding protein; Ras-induced senescence protein 1; p40BBP; Transmembrane protein 158; RIS1 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | K562 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TMEM158 |
| Gene Full Name | transmembrane protein 158 (gene/pseudogene) |
| Background | Constitutive activation of the Ras pathway triggers an irreversible proliferation arrest reminiscent of replicative senescence. Transcription of this gene is upregulated in response to activation of the Ras pathway, but not under other conditions that induce senescence. The encoded protein is similar to a rat cell surface receptor proposed to function in a neuronal survival pathway. An allelic polymorphism in this gene results in both functional and non-functional (frameshifted) alleles; the reference genome represents the functional allele. [provided by RefSeq, Jul 2015] |
| Function | Receptor for brain injury-derived neurotrophic peptide (BINP), a synthetic 13-mer peptide. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 30 kDa |
| PTM | N-glycosylated. [UniProt] |
