ARG42914
anti-TNFAIP8 antibody
anti-TNFAIP8 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TNFAIP8 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TNFAIP8 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 71-116 of Human TNFAIP8. |
| Conjugation | Un-conjugated |
| Alternate Names | Tumor necrosis factor alpha-induced protein 8; Head and neck tumor and metastasis-related protein; SCCS2; NDED; TNF alpha-induced protein 8; SCC-S2; GG2-1; MDC-3.13; TNF-induced protein GG2-1; NF-kappa-B-inducible DED-containing protein |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HEK293T, Raw264.7 and H9C2 | ||||
| Observed Size | ~ 23 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95379 Human Tumor necrosis factor alpha-induced protein 8 Swiss-port # Q921Z5 Mouse Tumor necrosis factor alpha-induced protein 8 |
|---|---|
| Gene Symbol | TNFAIP8 |
| Gene Full Name | tumor necrosis factor, alpha-induced protein 8 |
| Function | Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. [UniProt] |
| Cellular Localization | Cytoplasm. [UniProt] |
| Calculated MW | 23 kDa |
