ARG56847
anti-TNFSF13 / APRIL antibody
anti-TNFSF13 / APRIL antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TNFSF13 / APRIL |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TNFSF13 / APRIL |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 180-230 of Human TNFSF13 / APRIL. |
| Conjugation | Un-conjugated |
| Alternate Names | TALL2; ZTNF2; TRDL-1; TNF- and APOL-related leukocyte expressed ligand 2; CD256; APRIL; A proliferation-inducing ligand; TNF-related death ligand 1; UNQ383/PRO715; CD antigen CD256; Tumor necrosis factor ligand superfamily member 13; TALL-2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | Jurkat cell lysate |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75888 Human Tumor necrosis factor ligand superfamily member 13 |
|---|---|
| Gene Symbol | TNFSF13 |
| Gene Full Name | tumor necrosis factor (ligand) superfamily, member 13 |
| Background | The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010] |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. [UniProt] |
| Calculated MW | 27 kDa |
| PTM | The precursor is cleaved by furin. |
