ARG65293
anti-TPPP / p25 antibody
anti-TPPP / p25 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Signaling Transduction antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes TPPP / p25 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TPPP / p25 |
| Antigen Species | Human |
| Immunogen | C-DPSKDRAAKRLSLES |
| Conjugation | Un-conjugated |
| Alternate Names | TPPP1; TPPP; p25-alpha; p25; p24; Tubulin polymerization-promoting protein; 25 kDa brain-specific protein; p25alpha; TPPP/p25 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Microwaved or steamed tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by antigen affinity chromatography. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O94811 Human Tubulin polymerization-promoting protein Swiss-port # Q7TQD2 Mouse Tubulin polymerization-promoting protein |
|---|---|
| Gene Symbol | TPPP |
| Gene Full Name | tubulin polymerization promoting protein |
| Function | May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown. [UniProt] |
| Research Area | Signaling Transduction antibody |
| Calculated MW | 24 kDa |
| PTM | Poor substrate for GSK3 (By similarity). Phosphorylated by LIMK1 on serine residues. Phosphorylation may alter the tubulin polymerization activity. |
