ARG58762
anti-TREM1 antibody
anti-TREM1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TREM1 |
|---|---|
| Tested Reactivity | Ms, Rat |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TREM1 |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide corresponding to aa. 74-90 of Mouse TREM1 (FTRPSEVHMGKFTLKHD). |
| Conjugation | Un-conjugated |
| Alternate Names | TREM-1; CD antigen CD354; CD354; Triggering receptor expressed on monocytes 1; Triggering receptor expressed on myeloid cells 1 |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: By heat mediation. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA. |
| Preservative | 0.05% Thimerosal and 0.05% Sodium azide |
| Stabilizer | 5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9JKE2 Mouse Triggering receptor expressed on myeloid cells 1 |
|---|---|
| Gene Symbol | TREM1 |
| Gene Full Name | triggering receptor expressed on myeloid cells 1 |
| Background | This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
| Function | Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 26 kDa |
| PTM | Glycosylated. [UniProt] |
