ARG64976

anti-TREML1 antibody

anti-TREML1 antibody for Western blot and Human

Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes TREML1
Tested Reactivity Hu
Tested Application WB
Specificity This antibody may cross-react with mouse TREML1 (GeneID: 71326; MW: 34.28 kDa).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name TREML1
Antigen Species Human
Immunogen CGPAQNPPNNQTPS
Conjugation Un-conjugated
Alternate Names GLTL1825; dJ238O23.3; Trem-like transcript 1 protein; TLT-1; TLT1; PRO3438; Triggering receptor expressed on myeloid cells-like protein 1

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 340205 Human TREML1

Swiss-port # Q86YW5 Human Trem-like transcript 1 protein

Background TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM, Mar 2008]
Research Area Cell Biology and Cellular Response antibody; Immune System antibody; Signaling Transduction antibody
Calculated MW 33 kDa
PTM Phosphorylated on tyrosine residues.