ARG57532
anti-TRIAD3 antibody
anti-TRIAD3 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TRIAD3 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TRIAD3 |
| Antigen Species | Mouse |
| Immunogen | Synthetic peptide (15 aa) within aa. 120-170 of Mouse TRIAD3. |
| Conjugation | Un-conjugated |
| Alternate Names | Ubiquitin-conjugating enzyme 7-interacting protein 1; TRIAD3; AI647468; EC 6.3.2.-; F830018F18Rik; AU019462; E3 ubiquitin-protein ligase RNF216; UbcM4-interacting protein 83; Ubce7ip1; C86502; 2810055G22Rik; RING finger protein 216; Triad domain-containing protein 3; UIP83 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse heart. | ||||||||
| Observed Size | 95 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by ion exchange chromatography. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P58283 Mouse E3 ubiquitin-protein ligase RNF216 Swiss-port # Q9NWF9 Human E3 ubiquitin-protein ligase RNF216 |
|---|---|
| Gene Symbol | Rnf216 |
| Gene Full Name | ring finger protein 216 |
| Function | Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Promotes TNF and RIP mediated apoptosis (By similarity). [UniProt] |
| Calculated MW | 99 kDa |
| PTM | Auto-ubiquitinated. [UniProt] |
