ARG44964
anti-TRIM17 antibody
anti-TRIM17 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes TRIM17 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | TRIM17 |
| Antigen Species | Human |
| Epitope | PGLQKQDLCQ EHHEPLKLFC QKDQSPICVV CRESREHRLH RVLPAEEAVQ GYKLKLEEDM EYLREQITRT GNLQAREEQS LAEWQGKVKE RRERIVLEFE KMNLYLVEEE QRLLQALETE EEETASRLRE SVACLDRQGH SLELLLLQLE |
| Conjugation | Un-conjugated |
| Alternate Names | TRIM17; Tripartite Motif Containing 17; RBCC; Testis RING Finger Protein; RNF16; Terf; RING-Type E3 Ubiquitin Transferase TRIM17; Tripartite Motif-Containing Protein 17; E3 Ubiquitin-Protein Ligase TRIM17; RING Finger Protein Terf; Ring Finger Protein 16; Tripartite Motif-Containing 17; RING Finger Protein 16; EC 2.3.2.27; TERF |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TRIM17 |
|---|---|
| Gene Full Name | Tripartite Motif Containing 17 |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein is expressed almost exclusively in the testis, but its function is unknown. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Prevents the E3 ubiquitin-ligase activity of TRIM28 and its interaction with anti-apoptotic BCL2A1, blocking TRIM28 from ubiquitinating BCL2A1. [Uniprot] |
| Cellular Localization | Cytoplasm, Lysosome. [Uniprot] |
| Calculated MW | 54 kDa |
| PTM | Ubl conjugation. [Uniprot] |
