ARG44965
anti-TRIM34 / RNF21 antibody
anti-TRIM34 / RNF21 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes TRIM34 / RNF21 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | TRIM34 / RNF21 |
| Antigen Species | Human |
| Epitope | GEKLLLFCKE DRKVICWLCE RSQEHRGHHT VLTEEVFKEC QEKLQAVLKR LKKEEEEAEK LEADIREEKT SWKYQVQTER QRIQTEFDQL RSILNNEEQR ELQRLEEEEK KTLDKFAEAE |
| Conjugation | Un-conjugated |
| Alternate Names | TRIM34; Tripartite Motif Containing 34; RNF21; Interferon-Responsive Finger Protein 1; E3 Ubiquitin-Protein Ligase TRIM34; IFP1; Ring Finger Protein 21, Interferon-Responsive; Tripartite Motif-Containing 34; RING Finger Protein 21; EC 2.3.2.27; EC 6.3.2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TRIM34 |
|---|---|
| Gene Full Name | Tripartite Motif Containing 34 |
| Background | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. Expression of this gene is up-regulated by interferon. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from the upstream TRIM6 gene has also been observed, which results in a fusion product from these neighboring family members. [provided by RefSeq, Oct 2010] |
| Function | Promotes also the formation of multinucleated giant cells by means of cell fusion and phagocytosis in epithelial cells. [Uniprot] |
| Cellular Localization | Cytoplasm, Mitochondrion. [Uniprot] |
