ARG63271

anti-TRIM63 / MuRF1 antibody

anti-TRIM63 / MuRF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cell Biology and Cellular Response antibody; Gene Regulation antibody

Overview

Product Description Goat Polyclonal antibody recognizes TRIM63 / MuRF1
Tested Reactivity Hu
Predict Reactivity Cow, Dog
Tested Application IHC-P, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name TRIM63 / MuRF1
Antigen Species Human
Immunogen DYKSSLIQDGNPM-C
Conjugation Un-conjugated
Alternate Names E3 ubiquitin-protein ligase TRIM63; Muscle-specific RING finger protein 1; EC 6.3.2.-; MURF2; MURF1; MuRF-1; Striated muscle RING zinc finger protein; SMRZ; RNF28; RING finger protein 28; Tripartite motif-containing protein 63; MuRF1; IRF; Iris RING finger protein

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1 - 2 µg/ml
WB0.1 µg/ml
Application Note IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 84676 Human TRIM63

Swiss-port # Q969Q1 Human E3 ubiquitin-protein ligase TRIM63

Background This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. [provided by RefSeq, Feb 2012]
Research Area Cell Biology and Cellular Response antibody; Gene Regulation antibody
Calculated MW 40 kDa