ARG44970
anti-TRIM65 antibody
anti-TRIM65 antibody for Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes TRIM65 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Target Name | TRIM65 |
| Antigen Species | Human |
| Epitope | DAERLKREAQ LRASLEVTQQ QATQAEGQLL ELRKQSSQIQ NSACILASWV SGKFSSLLQA LEIQHTTALR SIEVAKTQAL AQARDEEQRL RVHLEAVARH GCRIRELLEQ VDEQTFLQES QLLQPPGPLG PLTPLQWDED QQLGDLKQLL SRLCGLLLEE GSHPGAPAKP VDLAPVEAPG |
| Conjugation | Un-conjugated |
| Alternate Names | TRIM65; Tripartite Motif Containing 65; Tripartite Motif-Containing Protein 65; E3 Ubiquitin-Protein Ligase TRIM65; Tripartite Motif-Containing 65; 4732463G12Rik; EC 2.3.2.27 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | TRIM65 |
|---|---|
| Gene Full Name | Tripartite Motif Containing 65 |
| Background | Predicted to enable zinc ion binding activity. Involved in positive regulation of autophagy. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| Function | In addition, negatively regulates inflammasome activation by promoting 'lys48'-linked ubiquitination of NLRP3 which is critical for the inhibition of NLRP3 inflammasome activation in resting macrophages. [Uniprot] |
| Cellular Localization | Cytoplasm. [Uniprot] |
| PTM | Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation. [Uniprot] |
