ARG63815

anti-TRPC6 antibody

anti-TRPC6 antibody for Flow cytometry,Western blot and Human

Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes TRPC6
Tested Reactivity Hu
Predict Reactivity Cow, Dog, Pig
Tested Application FACS, WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name TRPC6
Antigen Species Human
Immunogen C-EKLSMEPNQEETN
Conjugation Un-conjugated
Alternate Names FSGS2; Transient receptor protein 6; TrpC6; Short transient receptor potential channel 6; TRP-6; TRP6

Application Instructions

Application Suggestion
Tested Application Dilution
FACS10 µg/ml
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7225 Human TRPC6

Swiss-port # Q9Y210 Human Short transient receptor potential channel 6

Background The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
Research Area Signaling Transduction antibody
Calculated MW 106 kDa
PTM Phosphorylated by FYN, leading to an increase of TRPC6 channel activity.