ARG55638

anti-TSLP antibody

anti-TSLP antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse

Overview

Product Description

Rabbit Polyclonal antibody recognizes TSLP

Tested Reactivity Hu, Ms
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TSLP
Antigen Species Human
Immunogen Synthetic peptide (19 aa) within aa. 40-90 of Human TSLP.
Conjugation Un-conjugated
Alternate Names Thymic stromal lymphopoietin

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF20 µg/ml
IHC-P2.5 µg/ml
WB0.5 - 2 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A-20 Cell Lysate

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS and 0.02% Sodium azide
Preservative 0.02% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 53603 Mouse TSLP

GeneID: 85480 Human TSLP

Swiss-port # Q969D9 Human Thymic stromal lymphopoietin

Swiss-port # Q9JIE6 Mouse Thymic stromal lymphopoietin

Gene Symbol TSLP
Gene Full Name thymic stromal lymphopoietin
Background This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Function Isoform 1: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells.

Isoform 2: May act as an antimicrobial peptide in the oral cavity and on the skin. [UniProt]
Calculated MW 18 kDa