ARG42447

anti-TSPAN7 antibody [B2D] (FITC)

anti-TSPAN7 antibody [B2D] (FITC) for Flow cytometry and Human

Overview

Product Description FITC-conjugated Mouse Monoclonal antibody [B2D] recognizes TSPAN7
Tested Reactivity Hu
Tested Application FACS
Specificity The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.
Host Mouse
Clonality Monoclonal
Clone B2D
Isotype IgG1
Target Name TSPAN7
Antigen Species Human
Immunogen Human T-ALL cell line THP-6.
Conjugation FITC
Alternate Names A15; CCG-B7; Tetraspanin-7; Transmembrane 4 superfamily member 2; CD antigen CD231; TM4SF2; Tspan-7; Cell surface glycoprotein A15; TM4SF2b; CD231; DXS1692E; Membrane component chromosome X surface marker 1; T-cell acute lymphoblastic leukemia-associated antigen 1; TALLA-1; MRX58; MXS1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS4 µl / 100 µl of whole blood or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7102 Human TSPAN7

Swiss-port # P41732 Human Tetraspanin-7

Gene Symbol TSPAN7
Gene Full Name tetraspanin 7
Background The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
Function May be involved in cell proliferation and cell motility. [UniProt]
Cellular Localization Membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 28 kDa