ARG55481
anti-TXNDC5 / EndoPDI antibody
anti-TXNDC5 / EndoPDI antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TXNDC5 / EndoPDI |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TXNDC5 / EndoPDI |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human TXNDC5 / EndoPDI. |
| Conjugation | Un-conjugated |
| Alternate Names | HCC2; ERp46; Thioredoxin domain-containing protein 5; HCC-2; Thioredoxin-like protein p46; UNQ364; ER protein 46; ERP46; PDIA15; ENDOPDI; STRF8; Endoplasmic reticulum resident protein 46 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | 293T | ||||||||
| Observed Size | ~ 50 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8NBS9 Human Thioredoxin domain-containing protein 5 Swiss-port # Q91W90 Mouse Thioredoxin domain-containing protein 5 |
|---|---|
| Gene Symbol | TXNDC5 |
| Gene Full Name | thioredoxin domain containing 5 (endoplasmic reticulum) |
| Background | This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010] |
| Function | Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody |
| Calculated MW | 48 kDa |
