ARG55481

anti-TXNDC5 / EndoPDI antibody

anti-TXNDC5 / EndoPDI antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes TXNDC5 / EndoPDI
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name TXNDC5 / EndoPDI
Antigen Species Human
Immunogen Recombinant protein of Human TXNDC5 / EndoPDI.
Conjugation Un-conjugated
Alternate Names HCC2; ERp46; Thioredoxin domain-containing protein 5; HCC-2; Thioredoxin-like protein p46; UNQ364; ER protein 46; ERP46; PDIA15; ENDOPDI; STRF8; Endoplasmic reticulum resident protein 46

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:100
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control 293T
Observed Size ~ 50 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 105245 Mouse TXNDC5

GeneID: 81567 Human TXNDC5

Swiss-port # Q8NBS9 Human Thioredoxin domain-containing protein 5

Swiss-port # Q91W90 Mouse Thioredoxin domain-containing protein 5

Gene Symbol TXNDC5
Gene Full Name thioredoxin domain containing 5 (endoplasmic reticulum)
Background This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream MUTED (muted homolog) gene. [provided by RefSeq, Dec 2010]
Function Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide-isomerase deficiency in yeast (By similarity). [UniProt]
Research Area Cell Biology and Cellular Response antibody; Cell Death antibody; Signaling Transduction antibody
Calculated MW 48 kDa