ARG57843
anti-TXNRD2 antibody
anti-TXNRD2 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes TXNRD2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | TXNRD2 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human TXNRD2. |
| Conjugation | Un-conjugated |
| Alternate Names | TR-beta; Thioredoxin reductase 2, mitochondrial; EC 1.8.1.9; TR; Thioredoxin reductase TR3; SelZ; Selenoprotein Z; SELZ; TR3; TRXR2; TR-BETA |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | HepG2 | ||||||||
| Observed Size | ~ 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9JLT4 Mouse Thioredoxin reductase 2, mitochondrial Swiss-port # Q9NNW7 Human Thioredoxin reductase 2, mitochondrial |
|---|---|
| Gene Symbol | TXNRD2 |
| Gene Full Name | thioredoxin reductase 2 |
| Background | This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013] |
| Function | Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling. [UniProt] |
| Cellular Localization | Mitochondrion. [UniProt] |
| Calculated MW | 57 kDa |
