ARG23285
anti-Talin 2 antibody [53.8]
anti-Talin 2 antibody [53.8] for ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rabbit
Overview
| Product Description | Mouse Monoclonal antibody [53.8] recognizes Talin 2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rb |
| Tested Application | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 53.8 |
| Isotype | IgG2b |
| Target Name | Talin 2 |
| Antigen Species | Human |
| Immunogen | Recombinant Mouse Talin 2. (aa. 2300-2542) |
| Conjugation | Un-conjugated |
| Alternate Names | Talin-2; ILWEQ |
Application Instructions
| Application Suggestion |
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| Application Note | ICC/IF: Methanol treatment is required prior to antibody staining. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% Sodium azide. |
| Preservative | 0.09% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | TLN2 |
| Gene Full Name | talin 2 |
| Background | This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008] |
| Function | As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). [UniProt] |
| Calculated MW | 272 kDa |
