ARG64299

anti-Thyroid Hormone Receptor alpha antibody

anti-Thyroid Hormone Receptor alpha antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes Thyroid Hormone Receptor alpha
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Cow, Dog, Pig
Tested Application IHC-P, WB
Specificity This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB.
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name Thyroid Hormone Receptor alpha
Antigen Species Human
Immunogen C-KEEMIRSLQQRP
Conjugation Un-conjugated
Alternate Names c-ERBA-1; c-erbA-1; Thyroid hormone receptor alpha; V-erbA-related protein 7; AR7; NR1A1; Nuclear receptor subfamily 1 group A member 1; ERBA1; CHNG6; THRA1; THRA2; ERB-T-1; c-erbA-alpha; ERBA; EAR7; EAR-7

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P3 - 5 µg/ml
WB0.5 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7067 Human THRA

Swiss-port # P10827 Human Thyroid hormone receptor alpha

Background The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Research Area Gene Regulation antibody; Neuroscience antibody; Signaling Transduction antibody
Calculated MW 55 kDa