ARG64793
anti-U2AF1L4 antibody
anti-U2AF1L4 antibody for Western blot and Human
Gene Regulation antibody
Overview
Product Description | Goat Polyclonal antibody recognizes U2AF1L4 |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat, Dog |
Tested Application | WB |
Specificity | This antibody is expected to recognise both reported isoforms (NP_001035515.1 and NP_659424.2). No cross-reactivity with U2AF1 expected. |
Host | Goat |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | U2AF1L4 |
Antigen Species | Human |
Immunogen | C-EDGERAVAELSNR |
Conjugation | Un-conjugated |
Alternate Names | RNU2; U2 auxiliary factor 26; U2AF1-like 4; Splicing factor U2AF 26 kDa subunit; U2; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1L3; U2AF1L3V1; U2AF1-like protein 3; U2af26; U2AF1RS3; U2AF1-RS3 |
Application Instructions
Application Suggestion |
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Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified from goat serum by antigen affinity chromatography. |
Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
Preservative | 0.02% Sodium azide |
Stabilizer | 0.5% BSA |
Concentration | 0.5 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q8WU68 Human Splicing factor U2AF 26 kDa subunit |
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Gene Symbol | U2AF1L4 |
Gene Full Name | U2 small nuclear RNA auxiliary factor 1-like 4 |
Function | RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). [UniProt] |
Research Area | Gene Regulation antibody |
Calculated MW | 26 kDa |