ARG59957
anti-UBE2J2 antibody
anti-UBE2J2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes UBE2J2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | UBE2J2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-230 of Human UBE2J2 (NP_477515.2). |
| Conjugation | Un-conjugated |
| Alternate Names | EC 6.3.2.19; NCUBE2; Non-canonical ubiquitin-conjugating enzyme 2; PRO2121; NCUBE-2; Ubiquitin-conjugating enzyme E2 J2 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Mouse brain and U251 | ||||||||
| Observed Size | 29 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q6P073 Mouse Ubiquitin-conjugating enzyme E2 J2 Swiss-port # Q8N2K1 Human Ubiquitin-conjugating enzyme E2 J2 |
|---|---|
| Gene Symbol | UBE2J2 |
| Gene Full Name | ubiquitin-conjugating enzyme E2, J2 |
| Background | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] |
| Function | Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD) (By similarity). [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type IV membrane protein. [UniProt] |
| Calculated MW | 29 kDa |
