ARG42891
anti-UCHL5 / UCH37 antibody
anti-UCHL5 / UCH37 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF,Immunoprecipitation and Human,Mouse,Rat
Overview
Product Description | Rabbit Polyclonal antibody recognizes UCHL5 / UCH37 |
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Tested Reactivity | Hu, Ms, Rat |
Tested Application | ICC/IF, IHC-P, IP, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | UCHL5 / UCH37 |
Antigen Species | Human |
Immunogen | Synthetic peptide of Human UCHL5 / UCH37. |
Conjugation | Un-conjugated |
Alternate Names | UCH-L5; CGI-70; UCH37; INO80R; Ubiquitin thioesterase L5; Ubiquitin C-terminal hydrolase UCH37; Ubiquitin carboxyl-terminal hydrolase isozyme L5; EC 3.4.19.12 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
Positive Control | HeLa | ||||||||||
Observed Size | ~ 39 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | 50 nM Tris-Glycine (pH 7.4), 0.15M NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
Preservative | 0.01% Sodium azide |
Stabilizer | 40% Glycerol and 0.05% BSA |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9WUP7 Mouse Ubiquitin carboxyl-terminal hydrolase isozyme L5 Swiss-port # Q9Y5K5 Human Ubiquitin carboxyl-terminal hydrolase isozyme L5 |
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Gene Symbol | UCHL5 |
Gene Full Name | ubiquitin carboxyl-terminal hydrolase L5 |
Function | Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. [UniProt] |
Cellular Localization | Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus. [UniProt] |
Calculated MW | 38 kDa |