ARG44366

anti-USP53 antibody

anti-USP53 antibody for ICC/IF,Western blot and Human,Mouse

Overview

Product Description Rabbit Polyclonal antibody recognizes USP53
Tested Reactivity Hu, Ms
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name USP53
Antigen Species Human
Immunogen Human USP53 recombinant protein (a.a. sequence: 495-582).
Conjugation Un-conjugated
Alternate Names USP53; Ubiquitin Specific Peptidase 53; KIAA1350; Inactive Ubiquitin Carboxyl-Terminal Hydrolase 53; Inactive Ubiquitin-Specific Peptidase 53; Ubiquitin Specific Protease 53; Ubiquitin Specific Proteinase 53; PFIC7

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS, 0.05% Proclin300 and 50% Glycerol.
Preservative 0.05% Proclin300
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54532 Human USP53

GeneID: 99526 Mouse USP53

Swiss-port # P15975 Mouse Inactive ubiquitin carboxyl-terminal hydrolase 53

Swiss-port # Q70EK8 Human Inactive ubiquitin carboxyl-terminal hydrolase 53

Gene Symbol USP53
Gene Full Name Ubiquitin Specific Peptidase 53
Background Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential and neuron apoptotic process. Predicted to be located in bicellular tight junction. Predicted to be active in cell-cell junction.
Function Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions. Has no peptidase activity.
Cellular Localization Cell junction, Tight junction
Calculated MW 121 kDa