ARG67121
anti-USP53 antibody
anti-USP53 antibody for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes USP53 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | USP53 |
| Antigen Species | Human |
| Immunogen | Human USP53 synthesized peptide |
| Conjugation | Un-conjugated |
| Alternate Names | USP53; Ubiquitin Specific Peptidase 53; KIAA1350; Inactive Ubiquitin Carboxyl-Terminal Hydrolase 53; Inactive Ubiquitin-Specific Peptidase 53; Ubiquitin Specific Protease 53; Ubiquitin Specific Proteinase 53; PFIC |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by antigen-affinity chromatography. |
| Buffer | PBS (pH 7.4), 0.02% Sodium azide, 0.5% BSA and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA and 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q70EK8 Human Inactive ubiquitin carboxyl-terminal hydrolase 53 |
|---|---|
| Gene Symbol | USP53 |
| Gene Full Name | Ubiquitin Specific Peptidase 53 |
| Background | Predicted to enable thiol-dependent deubiquitinase. Predicted to be involved in response to auditory stimulus and sensory perception of sound. Predicted to act upstream of or within action potential and neuron apoptotic process. Predicted to be located in bicellular tight junction. Predicted to be active in cell-cell junction. |
| Function | Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions. Has no peptidase activity. |
| Cellular Localization | Cell junction, Tight junction |
| Calculated MW | 121 kDa |
