ARG63328
anti-USP6 / TRE2 / TRE17 antibody
anti-USP6 / TRE2 / TRE17 antibody for Western blot and Human
Cell Biology and Cellular Response antibody; Gene Regulation antibody
Overview
| Product Description | Goat Polyclonal antibody recognizes USP6 / TRE2 / TRE17 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Goat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | USP6 / TRE2 / TRE17 |
| Antigen Species | Human |
| Immunogen | KISPLHHLQMECSP |
| Conjugation | Un-conjugated |
| Alternate Names | USP6-short; Ubiquitin-specific-processing protease 6; TRE17; TRESMCR; Ubiquitin carboxyl-terminal hydrolase 6; Proto-oncogene TRE-2; Deubiquitinating enzyme 6; Ubiquitin thioesterase 6; Tre-2; TRE2; EC 3.4.19.12; HRP1 |
Application Instructions
| Application Suggestion |
|
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|---|---|---|---|---|---|
| Application Note | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 0.5% BSA |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35125 Human Ubiquitin carboxyl-terminal hydrolase 6 |
|---|---|
| Gene Symbol | USP6 |
| Gene Full Name | ubiquitin specific peptidase 6 |
| Function | Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| Calculated MW | 159 kDa |
| PTM | Monubiquitinated; ubiquitination is calmodulin and calcium dependent. |
