ARG45051
anti-Uroplakin II / UPII antibody [RM507]
anti-Uroplakin II / UPII antibody [RM507] for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
| Product Description | Rabbit monoclonal [RM507] recognizes Uroplakin 2 . |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Specificity | This antibody reacts to human UPII (Uroplakin-2) |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | RM507 |
| Isotype | IgG |
| Target Name | Uroplakin 2 |
| Immunogen | A peptide corresponding to residues near the C-terminus of human UPII (Uroplakin-2). |
| Conjugation | Un-conjugated |
| Alternate Names | UPK2; Uroplakin 2; UPII; UP2; Uroplakin II; Uroplakin-2; MGC138598 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Stabilizer | 50% Glycerol, 1% BSA and 0.09% |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | UPK2 |
| Gene Full Name | Uroplakin 2 |
| Background | This gene encodes one of the proteins of the highly conserved urothelium-specific integral membrane proteins of the asymmetric unit membrane which forms urothelium apical plaques in mammals. The asymmetric unit membrane is believed to strengthen the urothelium by preventing cell rupture during bladder distention. The encoded protein is expressed in the peripheral blood of bladder cancer patients with transitional cell carcinomas.[provided by RefSeq, Sep 2009] |
| Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM. [Uniprot] |
| Cellular Localization | Cell membrane, Membrane. [Uniprot] |
| PTM | Cleavage on pair of basic residues, Glycoprotein. [Uniprot] |
