ARG55008
anti-VAPB antibody
anti-VAPB antibody for Western blot and Human,Rat
Cancer antibody; Metabolism antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes VAPB |
|---|---|
| Tested Reactivity | Hu, Rat |
| Predict Reactivity | Bov, Pig |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | VAPB |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 126-139 (Center) of Human VAPB. |
| Conjugation | Un-conjugated |
| Alternate Names | Vesicle-associated membrane protein-associated protein B/C; ALS8; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAMP-B; VAP-B; VAP-B/VAP-C |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95292 Human Vesicle-associated membrane protein-associated protein B/C Swiss-port # Q9Z269 Rat Vesicle-associated membrane protein-associated protein B |
|---|---|
| Gene Symbol | VAPB |
| Gene Full Name | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| Background | The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking. [provided by RefSeq, Jul 2008] |
| Function | Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation. [UniProt] |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Present in mitochondria-associated membranes that are endoplasmic reticulum membrane regions closely apposed to the outer mitochondrial membrane. |
| Research Area | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| Calculated MW | 27 kDa |
