ARG63329

anti-VAV2 antibody

anti-VAV2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody

Overview

Product Description Goat Polyclonal antibody recognizes VAV2
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Dog, Pig
Tested Application IHC-P, WB
Specificity This antobody is expected to recognise both reported isoforms (NP_001127870.1 and NP_003362.2).
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name VAV2
Antigen Species Human
Immunogen ETEAKYYRTLEDIEC
Conjugation Un-conjugated
Alternate Names Guanine nucleotide exchange factor VAV2; VAV-2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P2.5 µg/ml
WB1 - 1.5 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by antigen affinity chromatography.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7410 Human VAV2

Swiss-port # P52735 Human Guanine nucleotide exchange factor VAV2

Background VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Research Area Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
Calculated MW 101 kDa
PTM Phosphorylated on tyrosine residues in response to FGR activation.