ARG53727
anti-VPAC2 antibody [SP235]
anti-VPAC2 antibody [SP235] for Flow cytometry,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody
Publication2
Overview
| Product Description | Rabbit Monoclonal antibody [SP235] recognizes VPAC2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, IHC-P, WB |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SP235 |
| Isotype | IgG |
| Target Name | VPAC2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide LQFHRGSRAQSFLQTETSVI corresponds to amino acids 419–428 of the human VPAC2. |
| Conjugation | Un-conjugated |
| Alternate Names | PACAP-R3; VPAC2; Vasoactive intestinal polypeptide receptor 2; DUP7q36.3; Pituitary adenylate cyclase-activating polypeptide type III receptor; VIP-R-2; C16DUPq36.3; PACAP type III receptor; VPCAP2R; VPAC2R; Helodermin-preferring VIP receptor; PACAP-R-3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Tonsil |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by protein A/G |
| Buffer | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| Preservative | < 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | VIPR2 |
| Gene Full Name | vasoactive intestinal peptide receptor 2 |
| Background | This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011] |
| Function | This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. [UniProt] |
| Cellular Localization | Cytoplasm, Membrane |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Controls and Markers antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 49 kDa |
Specific References
Postmenopausal osteoporosis is associated with the regulation of SP, CGRP, VIP, and NPY.
WB / Rat
Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model.
WB / Rat
