ARG55011
anti-VSIG4 antibody
anti-VSIG4 antibody for Western blot and Human
Immune System antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes VSIG4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | VSIG4 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 308-335 (C-terminus) of Human VSIG4. |
| Conjugation | Un-conjugated |
| Alternate Names | Z39IG; Protein Z39Ig; CRIg; V-set and immunoglobulin domain-containing protein 4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | NCI-H292 |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9Y279 Human V-set and immunoglobulin domain-containing protein 4 |
|---|---|
| Gene Symbol | VSIG4 |
| Gene Full Name | V-set and immunoglobulin domain containing 4 |
| Background | This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010] |
| Function | Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Research Area | Immune System antibody |
| Calculated MW | 44 kDa |
