ARG57063

anti-VTA1 antibody [14G10]

anti-VTA1 antibody [14G10] for Flow cytometry,ICC/IF,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [14G10] recognizes VTA1
Tested Reactivity Hu
Tested Application FACS, ICC/IF, WB
Host Mouse
Clonality Monoclonal
Clone 14G10
Isotype IgG1, kappa
Target Name VTA1
Antigen Species Human
Immunogen Recombinant fragment around aa. 1-307 of Human VTA1.
Conjugation Un-conjugated
Alternate Names DRG1; HSPC228; Vacuolar protein sorting-associated protein VTA1 homolog; SKD1-binding protein 1; LYST-interacting protein 5; C6orf55; LIP5; SBP1; My012; Dopamine-responsive gene 1 protein; DRG-1

Application Instructions

Application Suggestion
Tested Application Dilution
FACS2-5 μg per 1*10^6 cells
ICC/IF1:100 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51534 Human VTA1

Swiss-port # Q9NP79 Human Vacuolar protein sorting-associated protein VTA1 homolog

Gene Symbol VTA1
Gene Full Name vesicle (multivesicular body) trafficking 1
Background C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]
Function Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. [UniProt]
Calculated MW 34 kDa