ARG55017

anti-WDR82 antibody

anti-WDR82 antibody for Western blot,ICC/IF and Human

Gene Regulation antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes WDR82
Tested Reactivity Hu
Predict Reactivity Ms
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name WDR82
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 12-46 (N-terminus) of Human WDR82.
Conjugation Un-conjugated
Alternate Names PRO34047; Swd2; Protein TMEM113; WD repeat-containing protein 82; MST107; MSTP107; PRO2730; TMEM113; SWD2; WDR82A

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:25
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SH-SY5Y

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 80335 Human WDR82

Swiss-port # Q6UXN9 Human WD repeat-containing protein 82

Gene Symbol WDR82
Gene Full Name WD repeat domain 82
Background TMEM113 (WDR82) is a component of the mammalian SET1A (MIM 611052)/SET1B (MIM 611055) histone H3-Lys4 methyltransferase complexes (Lee and Skalnik, 2005 [PubMed 16253997]; Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Jul 2010]
Function Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2A). Component of PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. [UniProt]
Cellular Localization Nucleus Note=Associates with chromatin
Research Area Gene Regulation antibody
Calculated MW 35 kDa