ARG41813
anti-WFDC2 / HE4 antibody
anti-WFDC2 / HE4 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes WFDC2 / HE4 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | WFDC2 / HE4 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human WFDC2 / HE4. |
| Conjugation | Un-conjugated |
| Alternate Names | HE4; dJ461P17.6; WAP5; Putative protease inhibitor WAP5; Major epididymis-specific protein E4; WAP four-disulfide core domain protein 2; Epididymal secretory protein E4; EDDM4 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Human ovary cancer | ||||||||
| Observed Size | ~ 19 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q14508 Human WAP four-disulfide core domain protein 2 |
|---|---|
| Gene Symbol | WFDC2 |
| Gene Full Name | WAP four-disulfide core domain 2 |
| Background | This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008] |
| Function | Broad range protease inhibitor. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Calculated MW | 13 kDa |
