ARG55019
anti-WSB2 antibody
anti-WSB2 antibody for Western blot and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes WSB2 |
---|---|
Tested Reactivity | Hu |
Predict Reactivity | Ms, Bov |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | WSB2 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 375-404 (C-terminus) of Human WSB2. |
Conjugation | Un-conjugated |
Alternate Names | WSB-2; CS box-containing WD protein; WD repeat and SOCS box-containing protein 2; SBA2 |
Application Instructions
Application Suggestion |
|
||||
---|---|---|---|---|---|
Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | HeLa |
Properties
Form | Liquid |
---|---|
Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Buffer | PBS and 0.09% (W/V) Sodium azide |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9NYS7 Human WD repeat and SOCS box-containing protein 2 |
---|---|
Gene Symbol | WSB2 |
Gene Full Name | WD repeat and SOCS box containing 2 |
Background | This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013] |
Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. [UniProt] |
Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Developmental Biology antibody |
Calculated MW | 45 kDa |