ARG41295
anti-YARS2 antibody
anti-YARS2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes YARS2 |
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Tested Reactivity | Hu |
Predict Reactivity | Ms, Rat |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | YARS2 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 399-427 of Human YARS2. |
Conjugation | Un-conjugated |
Alternate Names | Tyrosyl-tRNA synthetase; CGI-04; Tyrosine--tRNA ligase, mitochondrial; EC 6.1.1.1; TyrRS; MT-TYRRS; TYRRS; MLASA2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | K562 | ||||||
Observed Size | ~ 50 kDa |
Properties
Form | Liquid |
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Purification | This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide. |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q9Y2Z4 Human Tyrosine--tRNA ligase, mitochondrial |
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Gene Symbol | YARS2 |
Gene Full Name | tyrosyl-tRNA synthetase 2, mitochondrial |
Background | This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). [provided by RefSeq, Jan 2011] |
Function | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). [UniProt] |
Cellular Localization | Mitochondrion matrix. [UniProt] |
Calculated MW | 53 kDa |