ARG41295

anti-YARS2 antibody

anti-YARS2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes YARS2
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name YARS2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 399-427 of Human YARS2.
Conjugation Un-conjugated
Alternate Names Tyrosyl-tRNA synthetase; CGI-04; Tyrosine--tRNA ligase, mitochondrial; EC 6.1.1.1; TyrRS; MT-TYRRS; TYRRS; MLASA2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:10 - 1:50
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562
Observed Size ~ 50 kDa

Properties

Form Liquid
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51067 Human YARS2

Swiss-port # Q9Y2Z4 Human Tyrosine--tRNA ligase, mitochondrial

Gene Symbol YARS2
Gene Full Name tyrosyl-tRNA synthetase 2, mitochondrial
Background This gene encodes a mitochondrial protein that catalyzes the attachment of tyrosine to tRNA(Tyr). Mutations in this gene are associated with myopathy with lactic acidosis and sideroblastic anemia type 2 (MLASA2). [provided by RefSeq, Jan 2011]
Function Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). [UniProt]
Cellular Localization Mitochondrion matrix. [UniProt]
Calculated MW 53 kDa