ARG44547

anti-YTHDC1 antibody

anti-YTHDC1 antibody for ICC/IF,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes YTHDC1
Tested Reactivity Hu, Ms, Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name YTHDC1
Antigen Species Human
Immunogen Human YTHDC1 fusion protein
Conjugation Un-conjugated
Alternate Names YTHDC1; YTH N6-Methyladenosine RNA Binding Protein C1; YT521-B; YT521; YTH Domain Containing 1; KIAA1966; YTH Domain-Containing Protein 1; Splicing Factor YT521; Putative Splicing Factor YT521; Splicing Factor YT521-B

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:50- 1:200
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 85, 110 kDa

Properties

Form Liquid
Purification Affinity Purified
Buffer PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol.
Preservative 0.05% Sodium azide
Stabilizer 40% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 170956 Rat YTHDC1

GeneID: 231386 Mouse YTHDC1

GeneID: 91746 Human YTHDC1

Gene Symbol YTHDC1
Gene Full Name YTH N6-Methyladenosine RNA Binding Protein C1
Background Enables N6-methyladenosine-containing RNA binding activity. Involved in mRNA export from nucleus; mRNA splice site selection; and regulation of gene expression. Located in nuclear speck and plasma membrane.
Function Regulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs.
Cellular Localization Nucleus
Calculated MW 85 kDa
PTM Isopeptide bond, Phosphoprotein, Ubl conjugation