ARG45120
anti-YTHDF2 antibody
anti-YTHDF2 antibody for Flow cytometry,ICC/IF,Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes YTHDF2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | YTHDF2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human YTHDF2. |
| Conjugation | Un-conjugated |
| Alternate Names | YTHDF2; YTH N6-Methyladenosine RNA Binding Protein F2; HGRG8; NY-REN-2; CAHL; YTH N(6)-Methyladenosine RNA Binding Protein 2; YTH N6-Methyladenosine RNA Binding Protein 2; YTH Domain-Containing Family Protein 2; High-Glucose-Regulated Protein 8; Renal Carcinoma Antigen NY-REN-2; CLL-Associated Antigen KW-14; YTH Domain Family, Member 2; DF2; YTH Domain Family; 9430020E02Rik |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Buffer | 0.9% NaCl, 0.2% Na2HPO4, 0.01% Sodium azide and 4% Trehalose. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 4% Trehalose |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q91YT7 Mouse YTH domain-containing family protein 2 Swiss-port # Q9Y5A9 Human YTH domain-containing family protein 2 |
|---|---|
| Gene Symbol | YTHDF2 |
| Gene Full Name | YTH N6-Methyladenosine RNA Binding Protein F2 |
| Background | This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Oct 2012] |
| Function | May also recognize and bind RNAs modified by C5-methylcytosine (m5C) and act as a regulator of rRNA processing. [Uniprot] |
| Cellular Localization | Cytoplasm, Nucleus. [Uniprot] |
| Calculated MW | 62 kDa |
| PTM | Acetylation, Phosphoprotein, Ubl conjugation. [Uniprot] |
