ARG55027

anti-ZNF281 antibody

anti-ZNF281 antibody for Western blot and Human,Mouse

Developmental Biology antibody; Gene Regulation antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes ZNF281
Tested Reactivity Hu, Ms
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ZNF281
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 416-450 (Center) of Human ZNF281.
Conjugation Un-conjugated
Alternate Names ZBP-99; GC-box-binding zinc finger protein 1; Transcription factor ZBP-99; Zinc finger protein 281; ZNP-99; Zinc finger DNA-binding protein 99

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse small intestine

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 23528 Human ZNF281

Swiss-port # Q9Y2X9 Human Zinc finger protein 281

Gene Symbol ZNF281
Gene Full Name zinc finger protein 281
Function Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G-rich box in the enhancer region of these genes. [UniProt]
Cellular Localization Nucleus.
Research Area Developmental Biology antibody; Gene Regulation antibody
Calculated MW 97 kDa