ARG41809

anti-ZNRF2 antibody

anti-ZNRF2 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes ZNRF2
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name ZNRF2
Antigen Species Human
Immunogen Synthetic peptide of Human ZNRF2.
Conjugation Un-conjugated
Alternate Names EC 6.3.2.-; E3 ubiquitin-protein ligase ZNRF2; Zinc/RING finger protein 2; RING finger protein 202; RNF202; Protein Ells2

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control HeLa
Observed Size ~ 25 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 223082 Human ZNRF2

GeneID: 387524 Mouse ZNRF2

Swiss-port # Q71FD5 Mouse E3 ubiquitin-protein ligase ZNRF2

Swiss-port # Q8NHG8 Human E3 ubiquitin-protein ligase ZNRF2

Gene Symbol ZNRF2
Gene Full Name zinc and ring finger 2, E3 ubiquitin protein ligase
Function May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. [UniProt]
Cellular Localization Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein. Note=Present in presynaptic plasma membranes in neurons. [UniProt]
Calculated MW 24 kDa