ARG66350
anti-acidic Cytokeratin antibody [SQab18100]
anti-acidic Cytokeratin antibody [SQab18100] for IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Recombinant Rabbit Monoclonal antibody [SQab18100] recognizes acidic Cytokeratin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Specificity | This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It also can be used in a cytokeratin cocktail with type II cytokeratin antibody. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SQab18100 |
| Isotype | IgG |
| Target Name | acidic Cytokeratin |
| Antigen Species | Human |
| Immunogen | Synthetic peptide within aa. 100-200 of Human Type I Cytokeratins. |
| Conjugation | Un-conjugated |
| Alternate Names | EPPK; Keratin, type I cytoskeletal 9; K9; Keratin-9; CK-9; Cytokeratin-9; KPP; K10; CK-10; BIE; Keratin, type I cytoskeletal 10; Cytokeratin-10; CK10; BCIE; Keratin-10; EHK; K12; CK-12; Cytokeratin-12; Keratin-12; Keratin, type I cytoskeletal 12; K13; Keratin, type I cytoskeletal 13; CK-13; Cytokeratin-13; WSN2; CK13; Keratin-13; K14; CK-14; Cytokeratin-14; Keratin, type I cytoskeletal 14; EBS3; EBS4; NFJ; Keratin-14; CK14; CK-15; K15; Keratin, type I cytoskeletal 15; Cytokeratin-15; Keratin-15; K1CO; CK15; KRT16A; K16; FNEPPK; Cytokeratin-16; PC1; K1CP; Keratin-16; CK-16; CK16; NEPPK; Keratin, type I cytoskeletal 16; CK-17; K17; PC2; Keratin, type I cytoskeletal 17; PC; Cytokeratin-17; Keratin-17; PCHC1; 39.1; Keratin, type I cytoskeletal 18; Cytokeratin-18; K18; CK-18; Cell proliferation-inducing gene 46 protein; Keratin-18; CYK18; Cytokeratin-19; K19; CK-19; K1CS; Keratin-19; CK19; Keratin, type I cytoskeletal 19; KRT21; CK20; K20; CD20; CK-20; Keratin-20; Cytokeratin-20; Keratin, type I cytoskeletal 20; Protein IT |
Application Instructions
| Application Suggestion |
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| Application Note | IHC-P: Antigen Retrieval: Heat mediated was performed using Tris/EDTA buffer (pH 9.0) * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A. |
| Buffer | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| Preservative | 0.01% Sodium azide |
| Stabilizer | 40% Glycerol and 0.05% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KRT9; KRT10; KRT12; KRT13; KRT14; KRT15; KRT16; KRT17; KRT18; KRT19; KRT20 |
| Gene Full Name | keratin 9, type I; keratin 10, type I; keratin 12, type I; keratin 13, type I; keratin 14, type I; keratin 15, type I; keratin 16, type I; keratin 17, type I; keratin 18, type I; keratin 19, type I; keratin 20, type I |
| Background | This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008] |
| Function | May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly. [UniProt] |
| Highlight | Related products: Anti-Rabbit IgG secondary antibodies; Related news: Cancer Pathology Markers (SQ clones) |
