ARG57930
anti-beta 2 Microglobulin antibody
anti-beta 2 Microglobulin antibody for Western blot,ICC/IF and Human,Mouse,Monkey
Overview
Product Description | Rabbit Polyclonal antibody recognizes beta 2 Microglobulin |
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Tested Reactivity | Hu, Ms, Mk |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | beta 2 Microglobulin |
Antigen Species | Human |
Immunogen | Recombinant fusion protein corresponding to aa. 21-119 of Human beta 2 Microglobulin (NP_004039.1). |
Conjugation | Un-conjugated |
Alternate Names | Beta-2-microglobulin |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | Mouse lung | ||||||
Observed Size | 12 kDa |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | B2M |
Gene Full Name | beta-2-microglobulin |
Background | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014] |
Function | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
Cellular Localization | Secreted. [UniProt] |
Calculated MW | 14 kDa |
PTM | Glycation of Ile-21 is observed in long-term hemodialysis patients. [UniProt] |