ARG21209
anti-beta 2 Microglobulin antibody [F21-21] (FITC)
anti-beta 2 Microglobulin antibody [F21-21] (FITC) for Flow cytometry,ICC/IF,Western blot and Chicken,Turkey
Overview
| Product Description | FITC-conjugated Mouse Monoclonal antibody [F21-21] recognizes beta 2 Microglobulin |
|---|---|
| Tested Reactivity | Chk, Turkey |
| Tested Application | FACS, ICC/IF, WB |
| Specificity | Chicken/Turkey β2-Microglobulin. The clone F21-21 also reacts with turkey β2-microglobulin. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | F21-21 |
| Isotype | IgG1, kappa |
| Target Name | beta 2 Microglobulin |
| Antigen Species | Chicken |
| Immunogen | Affinity purified chicken MHC-I molecules |
| Conjugation | FITC |
| Alternate Names | Beta-2-microglobulin |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | B2M |
|---|---|
| Gene Full Name | beta-2-microglobulin |
| Background | This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014] |
| Function | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. [UniProt] |
| Calculated MW | 14 kDa |
| PTM | Glycation of Ile-21 is observed in long-term hemodialysis patients. |
