ARG42704

anti-eIF2B alpha antibody

anti-eIF2B alpha antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes eIF2B alpha
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name eIF2B alpha
Antigen Species Human
Immunogen Synthetic peptide corresponding to a sequence of Human eIF2B alpha. (AESFKFVRLFPLNQQD)
Conjugation Un-conjugated
Alternate Names Translation initiation factor eIF-2B subunit alpha; EIF2B; eIF-2B GDP-GTP exchange factor subunit alpha; EIF2BA

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:150 - 1:500
ICC/IF1:200 - 1:1000
IHC-P1:200 - 1:1000
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size ~ 34 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer 0.2% Na2HPO4, 0.9% NaCl, 0.01% Sodium azide and 4% Trehalose.
Preservative 0.01% Sodium azide
Stabilizer 4% Trehalose
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1967 Human EIF2B1

GeneID: 209354 Mouse EIF2B1

GeneID: 64514 Rat EIF2B1

Gene Symbol EIF2B1
Gene Full Name eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
Background This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Oct 2009]
Function Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. [UniProt]
Calculated MW 34 kDa