ARG65446
anti-gamma Tubulin complex component 2 antibody [GCP2-01]
anti-gamma Tubulin complex component 2 antibody [GCP2-01] for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Pig,Rat
Controls and Markers antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [GCP2-01] recognizes gamma Tubulin complex component 2 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat, Pig |
| Tested Application | ICC/IF, IP, WB |
| Specificity | The clone GCP2-01 recognizes gamma-Tubulin complex component 2 (GCP2), a 95-103 kDa protein. It also recognizes phosphorylated GCP2. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | GCP2-01 |
| Isotype | IgG2b |
| Target Name | gamma Tubulin complex component 2 |
| Antigen Species | Mouse |
| Immunogen | GST-fusion protein containing amino acids 2-194 of mouse GCP2 |
| Conjugation | Un-conjugated |
| Alternate Names | GCP2; Grip103; h103p; hGrip103; GCP-2; hGCP2; hSpc97; SPBC97; Gamma-ring complex protein 103 kDa; Gamma-tubulin complex component 2; Spc97p; Spindle pole body protein Spc97 homolog |
Application Instructions
| Application Suggestion |
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| Application Note | WB: Used with reducing conditions. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from cell culture supernatant by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | Tubgcp2 |
| Gene Full Name | tubulin, gamma complex associated protein 2 |
| Background | gamma Tubulin complex component 2 (GCP2) is 95-103 kDa protein which associates with two molecules of gamma Tubulin and one molecule of gamma Tubulin complex component 3 (GCP3), to form the gamma Tubulin small complexes (gammaTuSCs). These complexes interact with GCP4, 5, and 6 to form the gamma Tubulin ring complexes (gammaTuRCs), which are embedded in the microtubule organizing center matrix where they nucleate microtubules. The gammaTuRCs are also involved in the regulation of microtubule plus and minus end dynamics. Components of gamma Tubulin complexes are highly conservative in eukaryotes. |
| Function | Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. [UniProt] |
| Research Area | Controls and Markers antibody; Signaling Transduction antibody |
| Calculated MW | 103 kDa |
Clone References
Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.
