ARG63027
anti-hCG beta antibody [HCG-61]
anti-hCG beta antibody [HCG-61] for ELISA,ICC/IF and Human
Cancer antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [HCG-61] recognizes hCG beta |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, ICC/IF |
| Specificity | The clone HCG-61 reacts with beta-subunit of human chorionic gonadotropin, a 40 kDa hormone. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum. The HCG-61 antibody reacts with association constant 5.1 x 1010 l/mol. Following cross-reactivity (%) was determined by classic double-antibody RIA using unlabelled hormones: beta-hCG (77), alpha-hCG (1.3), hLH (0.86), hFSH (< 0.5), hTSH (< 0.5). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HCG-61 |
| Isotype | IgG2b |
| Target Name | hCG beta |
| Antigen Species | Human |
| Immunogen | Human chorionic gonadotropin. |
| Conjugation | Un-conjugated |
| Alternate Names | hCGB; CGB5; CGB7; CGB3; Chorionic gonadotrophin chain beta; CGB8; CG-beta; Choriogonadotropin subunit beta |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified from ascites by protein-A affinity chromatography. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CGB |
| Gene Full Name | chorionic gonadotropin, beta polypeptide |
| Background | hCG is a protein of the molecular weight about 40 kDa. hCG belongs to the glycoprotein hormone family together with lutropin (LH), follitropin (FSH) and thyrotropin (TSH). hCG is synthesised by trophoblastic cells of the placenta during pregnancy and stimulates the growth of corpus luteum. The other hormones are produced by anterior pituitary gland. All these hormones are structurally related being composed of two noncovalently associated subunits alpha and beta. |
| Function | Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. [UniProt] |
| Cellular Localization | Secreted. [UniProt] |
| Research Area | Cancer antibody; Developmental Biology antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 18 kDa |
