ARG44290
anti-nSMase3 antibody
anti-nSMase3 antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes nSMase3 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IP, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | nSMase-3 |
| Antigen Species | Mouse |
| Immunogen | nSMase3 synthetic peptide |
| Conjugation | Un-conjugated |
| Alternate Names | SMPD4; Sphingomyelin Phosphodiesterase 4; KIAA1418; NSMASE3; NET13; Sphingomyelin Phosphodiesterase 4, Neutral Membrane (Neutral Sphingomyelinase-3); Neutral Sphingomyelinase III; Neutral Sphingomyelinase 3; FLJ20297; FLJ20756; NSMase-3; NSMASE-3; SKNY; Neutral Sphingomyelinase-3; EC 3.1.4.12; NEDMABA; NEDMEBA; NSMase3 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Antigen Affinity Purified |
| Buffer | PBS with 1 mg/ml BSA, 0.05% Sodium azide and 50% glycerol |
| Preservative | 0.05% Sodium azide |
| Stabilizer | 1 mg/ml BSA and 50% glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SMPD4 |
| Gene Full Name | Sphingomyelin Phosphodiesterase 4 |
| Background | The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. |
| Function | Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. |
| Cellular Localization | Cell membrane; Endoplasmic reticulum; Golgi apparatus; Membrane; Nucleus |
| Calculated MW | 98 kDa |
| PTM | Phosphoprotein |
