ARG57483
anti-p70 S6 Kinase antibody
anti-p70 S6 Kinase antibody for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes p70 S6 Kinase |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, ICC/IF, IHC-P, IP, WB |
| Specificity | This antibody detects endogenous levels of total p70 S6 Kinase. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | p70 S6 Kinase |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human p70 S6 Kinase. |
| Conjugation | Un-conjugated |
| Alternate Names | S6K-beta2; p70 ribosomal S6 kinase beta; Ribosomal protein S6 kinase beta-2; S6 kinase-related kinase; S6K-beta-2; p70-beta; p70 S6K-beta; p70 S6 kinase beta; p70S6Kb; STK14B; p70 S6KB; p70-S6K 2; P70-beta-1; P70-beta-2; S6K2; SRK; P70S6K2; KLS; Serine/threonine-protein kinase 14B; S6K-beta; P70-beta; p70(S6K)-beta; 70 kDa ribosomal protein S6 kinase 2; EC 2.7.11.1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS (pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9UBS0 Human Ribosomal protein S6 kinase beta-2 Swiss-port # Q9Z1M4 Mouse Ribosomal protein S6 kinase beta-2 |
|---|---|
| Gene Symbol | RPS6KB2 |
| Gene Full Name | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| Background | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015] |
| Function | Phosphorylates specifically ribosomal protein S6. [UniProt] |
| Calculated MW | 53 kDa |
| PTM | Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention. |
