ARG62611

anti-pS2 / Trefoil factor 1 antibody [pS2.1]

anti-pS2 / Trefoil factor 1 antibody [pS2.1] for Immunohistochemistry and Human

Signaling Transduction antibody

Overview

Product Description

Mouse Monoclonal antibody [pS2.1] recognizes pS2/Trefoil factor 1 

Tested Reactivity Hu
Tested Application IHC
Host Mouse
Clonality Monoclonal
Clone pS2.1
Isotype IgG1
Target Name pS2 / Trefoil factor 1
Antigen Species Human
Immunogen Synthetic peptide: KGCCFDDTVRGVPWCFYPNTIDVPPEEECEF, corresponding to amino acids 54-84 of Human pS2.
Conjugation Un-conjugated
Alternate Names D21S21; pNR-2; Trefoil factor 1; PNR-2; BCEI; hP1.A; HPS2; pS2; Polypeptide P1.A; HP1.A; Protein pS2; Breast cancer estrogen-inducible protein

Application Instructions

Application Note IHC: 1/10 - 1/500
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein G purified
Buffer 10mM PBS (pH 7.4), 0.2% BSA and 0.09% Sodium azide
Preservative 0.09% Sodium azide
Stabilizer 0.2% BSA
Concentration 0.2 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 7031 Human TFF1

Swiss-port # P04155 Human Trefoil factor 1

Gene Symbol TFF1
Gene Full Name trefoil factor 1
Background Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Function Stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. May inhibit the growth of calcium oxalate crystals in urine. [UniProt]
Research Area Signaling Transduction antibody
Calculated MW 9 kDa